Total Marks: 10 Due Data: Aug 12, 2020
Instructions:
Make sure that you upload the solution file
before due date. No assignment will be acceptable through e-mail after the due
date.
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Solution Guidelines
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To solve this assignment, you should
have good command over Topics.
·
This is not a group assignment; it is
an individual assignment so be careful and avoid copying others’ work
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Give the answer according to
question only and avoid irrelevant details.
Please
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If it is submitted after due date
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The file you uploaded does not open
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Cheating or copying of
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prohibited. The cheated or copied assignment will be marked ‘Zero’.
·
Answers should be précised and
clear with no useless material.
Assignment
Topic
Smith
and Waterman Algorithm:
Q.1: Define Smith
and waterman algorithm? Find the local alignment and alignment score of the
following sequences by applying smith and waterman algorithm. (5)
NOTE: Proper construct a complete matrix
with backtracking arrows.
Sequences:
1: ATGCGGTTATTGGAACCCTCAGTGACT
2: GCTAGTGACGTAGCGATAATGACG
Match Score: 1, Mismatch score: -1 and Gap
score: 0
Needleman
and Wunch Algorithm:
Q.2: Define Needleman
and Wunch algorithm? Find the global alignment and alignment score of the
following sequences by applying Needleman and Wunch algorithm. (5)
NOTE: Proper construct a complete matrix
with backtracking arrows.
Sequences:
1: ATGCGATGACGTGA
2: TAGCGATAATGACG
Match Score: 1, Mismatch score: -1 and Gap
score: 0
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